concept

TSG101

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TSG101: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

41Connections

0Hypotheses

0Analyses

24Outgoing

17Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	TSG101
Key Genes/Proteins	Actin, ALZHEIMER, ALZHEIMER'S DISEASE, CD63, CD81, CD9
Related Diseases	Als, Alzheimer
Related Pathways	oxidative stress response

Pathway Diagram

graph TD
    TSG101["TSG101"]
    TSG101 -->|"regulates"| Tau_Secretion["Tau Secretion"]
    TSG101 -->|"activates"| Alzheimer["Alzheimer"]
    TSG101 -->|"activates"| Tauopathy["Tauopathy"]
    TSG101 -->|"regulates"| RAB35["RAB35"]
    TSG101 -->|"activates"| TAU_PATHOLOGY["TAU PATHOLOGY"]
    TSG101 -->|"regulates"| AND["AND"]
    LYSOSOME["LYSOSOME"] -->|"regulates"| TSG101
    RAB7A["RAB7A"] -->|"regulates"| TSG101
    ALZHEIMER["ALZHEIMER"] -->|"activates"| TSG101
    RAB35 -->|"regulates"| TSG101
    TAUOPATHY["TAUOPATHY"] -->|"activates"| TSG101
    CHMP6["CHMP6"] -->|"regulates"| TSG101
    ENDOSOME["ENDOSOME"] -->|"regulates"| TSG101

Outgoing (24)

Target	Relation	Type	Str
Tau Degradation	regulates	process	0.80
MAPT	regulates	protein	0.75
Tau Secretion	regulates	process	0.75
Tauopathy	activates	disease	0.65
Alzheimer	activates	disease	0.65
Als	associated_with	disease	0.65
Alzheimer	stabilizes	disease	0.65
oxidative stress response	participates_in	pathway	0.65
Tauopathy	stabilizes	disease	0.65
EXOSOMES	associated_with	gene	0.60
Epithelial	associated_with	cell_type	0.60
RAB7A	regulates	gene	0.60
Actin	stabilizes	protein	0.60
Tau Protein	stabilizes	protein	0.60
Raf	regulates	protein	0.60
Actin	activates	protein	0.60
CHMP6	regulates	gene	0.60
ALZHEIMER'S DISEASE	activates	gene	0.60
ENDOSOME	regulates	gene	0.60
TAUOPATHY	activates	gene	0.60
TAU	regulates	gene	0.60
RAB35	regulates	gene	0.60
TAU PATHOLOGY	activates	gene	0.60
ubiquitin-proteasome	participates_in	pathway	0.55

Incoming (17)

Source	Relation	Type	Str
ALZHEIMER	stabilizes	gene	0.60
TAU	regulates	gene	0.60
TAUOPATHY	stabilizes	gene	0.60
CD63	activates	gene	0.60
CD9	activates	gene	0.60
RAB35	activates	gene	0.60
UGCG	activates	gene	0.60
RAB5	activates	gene	0.60
LYSOSOME	regulates	gene	0.60
RAB7A	regulates	gene	0.60
ALZHEIMER	activates	gene	0.60
RAB35	regulates	gene	0.60
TAUOPATHY	activates	gene	0.60
CHMP6	regulates	gene	0.60
ENDOSOME	regulates	gene	0.60
CD63	biomarker_for	gene	0.55
CD81	biomarker_for	gene	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TSG101 in their description or question text

No additional research found