Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SUBVENTRICULAR ZONE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SUBVENTRICULAR ZONE |
| Key Genes/Proteins | BECN1, GFAP, OLIG2 |
| Related Diseases | AGING, APOPTOSIS, AUTOPHAGY, NEURODEGENERATION, NEUROGENESIS |
graph TD
SUBVENTRICULAR_ZONE[SUBVENTRICULAR ZONE]
SUBVENTRICULAR_ZONE -->|causes| OLIG2[OLIG2]
SUBVENTRICULAR_ZONE -->|activates| BECN1[BECN1]
SUBVENTRICULAR_ZONE -->|causes| STRIATUM[STRIATUM]
NEURONS[NEURONS] -->|produces| SUBVENTRICULAR_ZONE
GBM[GBM] -->|expressed in| SUBVENTRICULAR_ZONE
schizophrenia[schizophrenia] -->|affects| SUBVENTRICULAR_ZONE| Target | Relation | Type | Str |
|---|---|---|---|
| STRIATUM | causes | brain_region | 0.65 |
| OLIG2 | causes | gene | 0.65 |
| BECN1 | activates | gene | 0.65 |
| OLIG2 | associated_with | gene | 0.45 |
| BECN1 | associated_with | gene | 0.45 |
| GFAP | associated_with | gene | 0.45 |
| TH | associated_with | gene | 0.45 |
| OLIGODENDROCYTE | associated_with | cell_type | 0.45 |
| NEUROGENESIS | associated_with | phenotype | 0.45 |
| NEURONS | associated_with | cell_type | 0.45 |
| AGING | associated_with | phenotype | 0.45 |
| NEURODEGENERATION | associated_with | disease | 0.45 |
| AUTOPHAGY | associated_with | phenotype | 0.45 |
| ROS | associated_with | phenotype | 0.45 |
| ASTROCYTES | associated_with | cell_type | 0.45 |
| STROKE | associated_with | disease | 0.45 |
| NEURON | associated_with | cell_type | 0.45 |
| ASTROCYTE | associated_with | cell_type | 0.45 |
| INTERNEURONS | associated_with | cell_type | 0.45 |
| MICROGLIA | associated_with | cell_type | 0.45 |
| APOPTOSIS | associated_with | phenotype | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| NEURONS | produces | cell_type | 0.65 |
| GBM | expressed_in | gene | 0.60 |
| schizophrenia | affects | disease | 0.60 |
| PARKINSON'S DISEASE | associated_with | disease | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SUBVENTRICULAR ZONE in their description or question text
No additional research found