Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC16A1-AS1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SLC16A1-AS1 |
| Key Genes/Proteins | AND, APOPTOSIS, App, CANCER, ERK, EXOSOMES |
| Related Diseases | Als, ALS, Cancer, Carcinoma, Glioblastoma |
| Related Pathways | Apoptosis, Cell Cycle |
graph TD
SLC16A1_AS1["SLC16A1-AS1"]
SLC16A1_AS1 -->|"inhibits"| Cancer["Cancer"]
SLC16A1_AS1 -->|"inhibits"| Glioblastoma["Glioblastoma"]
SLC16A1_AS1 -->|"expressed in"| Tumor["Tumor"]
SLC16A1_AS1 -->|"activates"| Carcinoma["Carcinoma"]
SLC16A1_AS1 -->|"regulates"| MIR_1269["MIR-1269"]
SLC16A1_AS1 -->|"interacts"| SLC16A1["SLC16A1"]
SLC16A1_AS1 -->|"inhibits"| GLIOBLASTOMA["GLIOBLASTOMA"]
LNCRNA["LNCRNA"] -->|"interacts"| SLC16A1_AS1
GBM["GBM"] -->|"interacts"| SLC16A1_AS1
APOPTOSIS["APOPTOSIS"] -->|"inhibits"| SLC16A1_AS1
RNA["RNA"] -->|"interacts"| SLC16A1_AS1
HNRNPA1["HNRNPA1"] -->|"activates"| SLC16A1_AS1
EXOSOMES["EXOSOMES"] -->|"activates"| SLC16A1_AS1
STAT3["STAT3"] -->|"activates"| SLC16A1_AS1| Target | Relation | Type | Str |
|---|---|---|---|
| ALS | associated_with | disease | 0.65 |
| Carcinoma | activates | disease | 0.65 |
| Tumor | expressed_in | disease | 0.65 |
| Tumor | activates | disease | 0.65 |
| Cancer | inhibits | disease | 0.65 |
| Glioblastoma | inhibits | disease | 0.65 |
| Als | associated_with | disease | 0.65 |
| SLC16A1 | interacts_with | gene | 0.60 |
| GLIOBLASTOMA | inhibits | gene | 0.60 |
| Apoptosis | inhibits | pathway | 0.60 |
| LNCRNA | inhibits | gene | 0.60 |
| T Cell | inhibits | cell_type | 0.60 |
| APOPTOSIS | inhibits | gene | 0.60 |
| SLC16A1 | activates | gene | 0.60 |
| METTL3 | activates | gene | 0.60 |
| IL-6 | activates | gene | 0.60 |
| Glycolysis | activates | pathway | 0.60 |
| EXOSOMES | activates | gene | 0.60 |
| Macrophage | activates | cell_type | 0.60 |
| Stat3 | activates | protein | 0.60 |
| Raf | activates | protein | 0.60 |
| ERK | activates | gene | 0.60 |
| MIR-1269 | regulates | gene | 0.60 |
| CANCER | inhibits | gene | 0.60 |
| SLC16A1 | inhibits | gene | 0.60 |
| Cell Cycle | inhibits | pathway | 0.60 |
| Ras | expressed_in | protein | 0.60 |
| LNCRNA | interacts_with | gene | 0.60 |
| STAT3 | activates | gene | 0.60 |
| HNRNPA1 | activates | gene | 0.60 |
| MIR-1269 | interacts_with | gene | 0.60 |
| GBM | interacts_with | gene | 0.60 |
| Ras | interacts_with | protein | 0.60 |
| App | associated_with | protein | 0.60 |
| T Cell | expressed_in | cell_type | 0.55 |
| Macrophage | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| MIR-1269 | interacts_with | gene | 0.60 |
| AND | inhibits | gene | 0.60 |
| AND | expressed_in | gene | 0.60 |
| IL-6 | activates | gene | 0.60 |
| RAF | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| METTL3 | activates | gene | 0.60 |
| SLC16A1 | interacts_with | gene | 0.60 |
| GLIOBLASTOMA | inhibits | gene | 0.60 |
| SLC16A1 | activates | gene | 0.60 |
| LNCRNA | interacts_with | gene | 0.60 |
| GBM | interacts_with | gene | 0.60 |
| APOPTOSIS | inhibits | gene | 0.60 |
| RNA | interacts_with | gene | 0.60 |
| HNRNPA1 | activates | gene | 0.60 |
| EXOSOMES | activates | gene | 0.60 |
| STAT3 | activates | gene | 0.60 |
| RNA | activates | gene | 0.60 |
| LNCRNA | inhibits | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SLC16A1-AS1 in their description or question text
No additional research found