Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PGR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet.
No AI portrait yet
| Name | PGR |
| Key Genes/Proteins | AR, CNR1, ESR1, GRIK1, MAPK10, MAPT |
| Related Diseases | Triple-Negative Breast Cancer |
| Related Pathways | MAPK signaling, oxidative stress response |
Knowledge base pages for this entity
graph TD
PGR[PGR]
PGR -.biomarker for.-> Triple_Negative_Breast_Cancer[Triple-Negative Breast Cancer]
PGR -->|interacts| PIK3R1[PIK3R1]
PGR -->|participates in| oxidative_stress_response[oxidative stress response]
PGR -->|participates in| MAPK_signaling[MAPK signaling]
PGR -->|data_in| benchmark_ot_ad_answer_key_PGR[benchmark_ot_ad_answer_key:PGR]
AR[AR] -->|interacts| PGR
CNR1[CNR1] -->|interacts| PGR
GRIK1[GRIK1] -->|interacts| PGR
MAPK10[MAPK10] -->|interacts| PGR
MAPT[MAPT] -->|interacts| PGR
ESR1[ESR1] -.protects against.-> PGR
NR3C1[NR3C1] -.protects against.-> PGR
benchmark_ot_ad_answer_key_PGR -->|data_in| PGR| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:PGR | data_in | dataset_row | 0.00 |
| Triple-Negative Breast Cancer | biomarker_for | disease | 0.85 |
| PIK3R1 | interacts_with | gene | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| MAPK signaling | participates_in | pathway | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PGR in their description or question text
No additional research found