gene

MAP1LC3B2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MAP1LC3B2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

17Connections

0Hypotheses

0Analyses

5Outgoing

12Incoming

0Experiments

0Debates

Summary

Page for MAP1LC3B2 Gene

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🧬 Gene Info

Gene Symbol	MAP1LC3B2
Chromosome	12p12.1
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	testis but also present in neuronal tissues
Molecular Weight	15 kDa
Amino Acids	125 aa
Exons	8
Pathways	Autophagy
GeneCards	MAP1LC3B2
Human Protein Atlas	MAP1LC3B2
Associated Diseases	neurodegeneration
Interactions	AUTOPHAGY, GENES, NEURODEGENERATIVE DISORDERS, P62, VIRAL INFECTIONS
KG Connections	17 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

MAP1LC3B2 Gene

gene · 725 words

→

MAP1LC3B2 Protein

protein · 927 words

→

Pathway Diagram

graph TD
    MAP1LC3B2["MAP1LC3B2"]
    LC3["LC3"]
    MAP1LC3B2 -->|"expressed in"| LC3
    Autophagy(["Autophagy"])
    MAP1LC3B2 -->|"expressed in"| Autophagy
    neurodegeneration["neurodegeneration"]
    MAP1LC3B2 -->|"implicated in"| neurodegeneration
    TRIM["TRIM"]
    TRIM -->|"regulates"| MAP1LC3B2
    RAR_["RARalpha"]
    RAR_ -->|"binds"| MAP1LC3B2
    P62["P62"]
    P62 -->|"activates"| MAP1LC3B2
    ULK1["ULK1"]
    ULK1 -->|"expressed in"| MAP1LC3B2
    AUTOPHAGY["AUTOPHAGY"]
    AUTOPHAGY -->|"expressed in"| MAP1LC3B2
    style MAP1LC3B2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (5)

Target	Relation	Type	Str
Ms	activates	disease	0.65
AUTOPHAGY	activates	gene	0.60
Autophagy	activates	pathway	0.60
LC3	expressed_in	gene	0.60
Autophagy	expressed_in	pathway	0.60

Incoming (12)

Source	Relation	Type	Str
TRIM	regulates	protein	0.80
RARα	binds	protein	0.80
ATG7	causes	gene	0.60
TBK1	causes	gene	0.60
ATG4A	causes	gene	0.60
NEURODEGENERATIVE DISORDERS	activates	gene	0.60
VIRAL INFECTIONS	activates	gene	0.60
GENES	activates	gene	0.60
AUTOPHAGY	expressed_in	gene	0.60
AND	causes	gene	0.60
P62	activates	gene	0.60
ULK1	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MAP1LC3B2 in their description or question text

No additional research found