protein 927 words KG: MAP1LC3B2PROTEIN
Contents

MAP1LC3B2 Protein

🔬 Protein Info
Gene SymbolMAP1LC3B2
AliasesMAP1LC3B2PROTEIN
Chromosome12p12.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressiontestis but also present in neuronal tissues
Subcellular Localization</b></td><td>Cytoplasm, Autophagosome, Lysosome</td></tr>
Molecular Weight15 kDa
Amino Acids125 aa
Exons8
PathwaysAutophagy
GeneCardsMAP1LC3B2
Human Protein AtlasMAP1LC3B2
Associated Diseasesneurodegeneration
InteractionsAUTOPHAGY, GENES, NEURODEGENERATIVE DISORDERS, P62, VIRAL INFECTIONS
KG Connections17 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (7)

SASP-Mediated Complement Cascade Amplification
Score: 0.91
APOE-Dependent Autophagy Restoration
Score: 0.85
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (7)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed

Related Experiments (8)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (1 edges)

proteins-map1lc3b2-protein describes MAP1LC3B2PROTEIN

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