gene 725 words KG: MAP1LC3B2
Contents

MAP1LC3B2 Gene

🧬 Gene Info
Gene SymbolMAP1LC3B2
Chromosome12p12.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressiontestis but also present in neuronal tissues
Molecular Weight15 kDa
Amino Acids125 aa
Exons8
PathwaysAutophagy
GeneCardsMAP1LC3B2
Human Protein AtlasMAP1LC3B2
Associated Diseasesneurodegeneration
InteractionsAUTOPHAGY, GENES, NEURODEGENERATIVE DISORDERS, P62, VIRAL INFECTIONS
KG Connections17 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (3)

SASP-Mediated Complement Cascade Amplification
Score: 0.95
CYP46A1 Overexpression Gene Therapy
Score: 0.95
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (8)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (9)

Neurodegeneration
disease · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: expressed_in
Genes
index · KG edge: activates
ATG4A Gene
gene · KG edge: causes
ATG7 Gene
gene · KG edge: causes

Knowledge Graph (12 edges)

P62 activates MAP1LC3B2
ULK1 expressed_in MAP1LC3B2
MAP1LC3B2 expressed_in LC3
TRIM regulates MAP1LC3B2
RARα binds MAP1LC3B2
ATG7 causes MAP1LC3B2
TBK1 causes MAP1LC3B2
ATG4A causes MAP1LC3B2
AUTOPHAGY expressed_in MAP1LC3B2
MAP1LC3B2 expressed_in Autophagy

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