protein

INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

13Connections

0Hypotheses

0Analyses

7Outgoing

6Incoming

0Experiments

0Debates

Summary

Page for Insulin-Like Growth Factor 1 Receptor Protein

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🔬 Protein Info

Gene Symbol	INSULIN
Full Name	LIKE GROWTH FACTOR 1 RECEPTOR
GeneCards	INSULIN
Human Protein Atlas	INSULIN
Known Drugs/Compounds	semaglutide
Interactions	AKT, AMPK, AMYLOID, APP, CLU, EGFR
KG Connections	325 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR("INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR")
    INSULIN_LIKE_GROWTH_FACTOR_1("INSULIN-LIKE GROWTH FACTOR 1")
    INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR -->|"regulates"| INSULIN_LIKE_GROWTH_FACTOR_1
    inflammation(["inflammation"])
    INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR -->|"regulates"| inflammation
    INSULIN["INSULIN"]
    INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR -->|"regulates"| INSULIN
    INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR -->|"activates"| INSULIN_LIKE_GROWTH_FACTOR_1
    PDGF["PDGF"]
    INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR -->|"activates"| PDGF
    INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR -->|"activates"| INSULIN
    CYTOKINE["CYTOKINE"]
    INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR -->|"activates"| CYTOKINE
    Neuroinflammation["Neuroinflammation"]
    Neuroinflammation -->|"regulates"| INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR
    IGF1R["IGF1R"]
    IGF1R -->|"regulates"| INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR
    Pi3K(["Pi3K"])
    Pi3K -->|"activates"| INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR
    IGF1["IGF1"]
    IGF1 -->|"activates"| INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR
    IGF1R -->|"activates"| INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR
    EGR1("EGR1")
    EGR1 -->|"activates"| INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR

Outgoing (7)

Target	Relation	Type	Str
INSULIN-LIKE GROWTH FACTOR 1	regulates	protein	0.50
inflammation	regulates	pathway	0.50
INSULIN	regulates	concept	0.50
INSULIN-LIKE GROWTH FACTOR 1	activates	protein	0.50
PDGF	activates	concept	0.50
INSULIN	activates	concept	0.50
CYTOKINE	activates	concept	0.50

Incoming (6)

Source	Relation	Type	Str
Neuroinflammation	regulates	process	0.50
IGF1R	regulates	gene	0.50
Pi3K	activates	pathway	0.50
IGF1	activates	gene	0.50
IGF1R	activates	gene	0.50
EGR1	activates	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR in their description or question text

No additional research found