gene

CAV2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CAV2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

35Connections

0Hypotheses

0Analyses

24Outgoing

11Incoming

0Experiments

0Debates

Summary

Caveolin 2 - co-assembles with caveolin-1 to form caveolae, with distinct signaling roles in cells

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🧬 Gene Info

Gene Symbol	CAV2
Aliases	Caveolin 2
Chromosome	7q31.1
Function	Description
Primary Expression	Ubiquitous
Molecular Weight	18 kDa
Amino Acids	81 aa
Pathways	MAPK, PI3K
GeneCards	CAV2
Human Protein Atlas	CAV2
Associated Diseases	Als, Glaucoma, Ms
Interactions	ALS, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, CAV1, CAV2.3
KG Connections	35 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CAV2

gene · 1000 words

→

CAV2 Protein

protein · 605 words

→

Pathway Diagram

graph TD
    CAV2["CAV2"]
    Alzheimer{"Alzheimer"}
    CAV2 -->|"inhibits"| Alzheimer
    Ms{"Ms"}
    CAV2 -->|"inhibits"| Ms
    Als{"Als"}
    CAV2 -->|"activates"| Als
    Aging{"Aging"}
    CAV2 -->|"regulates"| Aging
    Cancer{"Cancer"}
    CAV2 -->|"regulates"| Cancer
    PIK3C3["PIK3C3"]
    CAV2 -->|"activates"| PIK3C3
    Mapk(["Mapk"])
    CAV2 -->|"activates"| Mapk
    TAU["TAU"]
    CAV2 -->|"inhibits"| TAU
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    CAV2 -->|"inhibits"| ALZHEIMER_S_DISEASE
    ALZHEIMER["ALZHEIMER"]
    CAV2 -->|"inhibits"| ALZHEIMER
    AND["AND"]
    CAV2 -->|"inhibits"| AND
    AMYLOID["AMYLOID"]
    CAV2 -->|"inhibits"| AMYLOID
    AGING["AGING"]
    AGING -->|"regulates"| CAV2
    PPP2R2A["PPP2R2A"]
    PPP2R2A -->|"activates"| CAV2
    CANCER["CANCER"]
    CANCER -->|"regulates"| CAV2
    style CAV2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (24)

Target	Relation	Type	Str
Aging	regulates	disease	0.65
Cancer	regulates	disease	0.65
Als	activates	disease	0.65
Glaucoma	causes	disease	0.65
Ms	causes	disease	0.65
Als	causes	disease	0.65
Alzheimer	inhibits	disease	0.65
Ms	inhibits	disease	0.65
ALZHEIMER	inhibits	gene	0.60
oxidative stress response	participates_in	pathway	0.60
AMYLOID	inhibits	gene	0.60
Mapk	activates	pathway	0.60
ALZHEIMER'S DISEASE	inhibits	gene	0.60
PIK3C3	activates	gene	0.60
TAU	inhibits	gene	0.60
Neuron	inhibits	cell_type	0.60
GENES	causes	gene	0.60
Amyloid	inhibits	pathway	0.60
Ca1	expressed_in	brain_region	0.55
Neuron	expressed_in	cell_type	0.55
CAV2.3	inhibits	protein	0.50
STING	co_discussed	gene	0.50
CAV2.3	co_discussed	protein	0.50
NEURON	co_discussed	gene	0.50

Incoming (11)

Source	Relation	Type	Str
TAU	inhibits	gene	0.60
ALZHEIMER'S DISEASE	inhibits	gene	0.60
OPTN	causes	gene	0.60
CAV1	associated_with	gene	0.60
ALS	interacts_with	gene	0.60
PPP2R2A	activates	gene	0.60
AGING	regulates	gene	0.60
CANCER	regulates	gene	0.60
CAV1	interacts_with	gene	0.60
ALZHEIMER	inhibits	gene	0.60
WAS	inhibits	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CAV2 in their description or question text

No additional research found