| Gene Symbol | TPP1 |
| Aliases | Page for TPP1 Gene, Tripeptidyl Peptidase 1 |
| Chromosome | 11p15.4 |
| Protein Family | S9 family serine proteases |
| Function | It displays tripeptidyl-peptidase activity, cleaving N-terminal tripeptides from various substrates[1]. |
| Molecular Weight | 59 kDa |
| Amino Acids | 563 aa |
| Exons | 13 |
| Pathways | Chaperone, Tdp-43, autophagy pathway, oxidative stress response |
| UniProt ID | O14773 |
| NCBI Gene ID | 1201 |
| Ensembl ID | ENSG00000142149 |
| OMIM | 607998 |
| GeneCards | TPP1 |
| Human Protein Atlas | TPP1 |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, Ataxia, Huntington, Neuroblastoma, Parkinson |
| Known Drugs/Compounds | rapamycin |
| Interactions | AIF1, amyotrophic lateral sclerosis, AR, ATG, ATG10, ATG12 |
| KG Connections | 212 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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