protein 620 words KG: MLKLPROTEIN
Contents

MLKL Protein

🔬 Protein Info
Gene SymbolMLKL
AliasesMLKLPROTEIN
Chromosome16q23.1
Protein FamilyRHIM domain-containing pseudo-kinase
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight~54 kDa
Amino Acids480 aa
Exons10
PathwaysAkt, Apoptosis, Autophagy, Cell Division, Ferroptosis
UniProt IDQ8TBX5
NCBI Gene ID83568
Ensembl IDENSG00000147854
GeneCardsMLKL
Human Protein AtlasMLKL
Associated DiseasesAls, Alzheimer's disease, autism, DEMYELINATION, disease
Known Drugs/CompoundsHSYA, metformin, METFORMIN, Necrosulfonamide, rapamycin, RAPAMYCIN
InteractionsACSL4, Actin, AD, AIF, AIM2, AKT
KG Connections1241 knowledge graph edges
DatabasesGeneCardsHPASTRING

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