| Gene Symbol | GSDMD |
| Aliases | GSDMDPROTEIN |
| Function | is a gene encoding a key executor of pyroptotic cell death |
| Primary Expression | hippocampus, temporal lobe, cortex, Substantia Nigra, Ca1 |
| Molecular Weight | 56 kDa |
| Amino Acids | 484 aa |
| Pathways | Apoptosis, Ferroptosis, Inflammasome, Necroptosis, Oxidative Stress |
| GeneCards | GSDMD |
| Human Protein Atlas | GSDMD |
| Linker Region | Recognition site for caspase cleavage (D275↓) |
| Associated Diseases | Als, Alzheimer, Alzheimer's disease, amyotrophic lateral sclerosis, autism |
| Known Drugs/Compounds | curcumin, natural products, Pterostilbene, Qingqi Liangying Formula, XHP |
| Interactions | ABCG2, ACSL4, Actin, AGING, AIF, AIM2 |
| KG Connections | 853 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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