Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PTEROSTILBENE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | PTEROSTILBENE |
graph TD
PTEROSTILBENE[PTEROSTILBENE]
PTEROSTILBENE -->|binds| NLRP3[NLRP3]
PTEROSTILBENE -->|modulates| Cholinergic_Pathway[Cholinergic Pathway]
PTEROSTILBENE -->|treats| NAFLD[NAFLD]
PTEROSTILBENE -->|treats| Cognitive_Impairment[Cognitive Impairment]
PTEROSTILBENE -->|activates| NFE2L2[NFE2L2]
PTEROSTILBENE -->|inhibits| CASP1[CASP1]
PTEROSTILBENE -->|inhibits| GSDMD[GSDMD]
PTEROSTILBENE -->|upregulates| Acetylcholine[Acetylcholine]
PTEROSTILBENE -->|upregulates| CHAT[CHAT]| Target | Relation | Type | Str |
|---|---|---|---|
| NLRP3 | binds | gene | 0.95 |
| NLRP3 | inhibits | gene | 0.95 |
| Cognitive Impairment | treats | disease | 0.95 |
| Cholinergic Pathway | modulates | pathway | 0.95 |
| NAFLD | treats | disease | 0.95 |
| NFE2L2 | activates | gene | 0.90 |
| CASP1 | inhibits | gene | 0.90 |
| GSDMD | inhibits | gene | 0.90 |
| Acetylcholine | upregulates | biomarker | 0.90 |
| CHAT | upregulates | gene | 0.90 |
| AMPK | activates | protein | 0.90 |
| Pyroptosis | inhibits | process | 0.90 |
| Neuroinflammation | inhibits | process | 0.90 |
| SREBP1C | downregulates | gene | 0.88 |
| MTORC1 | inhibits | protein | 0.88 |
| Alzheimer's disease | protects_against | disease | 0.70 |
| inflammation | regulates | process | 0.70 |
| oxidative stress | regulates | process | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PTEROSTILBENE in their description or question text
No additional research found