protein 802 words KG: FYCO1PROTEIN
Contents

FYCO1 Protein — FYVE and Coiled-Coil Domain Containing 1

🔬 Protein Info
Gene SymbolFYCO1
Full NameFYVE and Coiled-Coil Domain Containing 1
Chromosome3p21.2
FunctionFYCO1 encodes a autophagy adapter protein that links autophagosomes to the microtubule-based transport machinery.
Primary Expressionthe lens, and mutations cause congenital cataract, often accompanying spastic paraplegia in SPG59
PathwaysmTOR, mtor
UniProt IDQ9BQR1
NCBI Gene ID79443
Ensembl IDENSG00000164120
OMIM607781
GeneCardsFYCO1
Human Protein AtlasFYCO1
Associated DiseasesCancer, Cardiovascular, Ischemia, Ms, Neurodegeneration, Parkinson
Known Drugs/Compoundsrapamycin
InteractionsAMPK, AMYLOID, AND, APOPTOSIS, AR, ATG
KG Connections170 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (14)

Purinergic Signaling Polarization Control
Score: 0.71
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
APOE-Dependent Autophagy Restoration
Score: 0.85
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78

Related Analyses (10)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Alpha-Synuclein Seeding Assays (RT-QuIC and PMCA)
biomarker · Pages share 3 hypotheses
IL-6 (Interleukin-6) in Neurodegeneration
biomarker · Pages share 3 hypotheses
Cell-Free DNA Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses
Exosomal Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)