protein 748 words KG: PEN2
Contents

Presenilin Enhancer 2 (PEN-2) Protein

🔬 Protein Info
Gene SymbolPSENEN
AliasesPresenilin Enhancer 2
Chromosome19q13.12
Protein FamilyPEN-2 family (γ-secretase complex)
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionEndoplasmic reticulum, Golgi apparatus, plasma membrane
Molecular Weight12 kDa
Amino Acids101 aa
PathwaysAngiogenesis
UniProt IDQ9NQ75
GeneCardsPSENEN
Human Protein AtlasPSENEN
Associated DiseasesAD, Als, Alzheimer, Alzheimer's disease, AMI
InteractionsA2M, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, APH1B, APOE
KG Connections94 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph (12 edges)

NCSTN interacts_with PEN2
FAS interacts_with PEN2
TNF interacts_with PEN2
LMNA interacts_with PEN2
APH1B interacts_with PEN2
APOE interacts_with PEN2
IL6 interacts_with PEN2
SREBF1 interacts_with PEN2
PSEN2 interacts_with PEN2
A2M interacts_with PEN2

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