Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MOB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MOB1 |
| Key Genes/Proteins | AND, CANCER, HDAC6, HIPPO, LATS1, MST1 |
| Related Diseases | Als, Cancer, Tumor |
| Related Pathways | Hippo Pathway, Oxidative Stress |
Knowledge base pages for this entity
graph TD
MOB1["MOB1"]
MOB1 -->|"regulates"| Cardiovascular["Cardiovascular"]
MOB1 -->|"activates"| Als["Als"]
MOB1 -->|"activates"| Cancer["Cancer"]
MOB1 -->|"activates"| Tumor["Tumor"]
MOB1 -->|"activates"| MST1["MST1"]
MOB1 -->|"activates"| HDAC6["HDAC6"]
MOB1 -->|"activates"| TAZ["TAZ"]
MOB1 -->|"activates"| ROS["ROS"]
OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"activates"| MOB1
AND["AND"] -->|"activates"| MOB1| Target | Relation | Type | Str |
|---|---|---|---|
| Tumor | activates | disease | 0.65 |
| Als | activates | disease | 0.65 |
| Cancer | activates | disease | 0.65 |
| ROS | activates | gene | 0.60 |
| CANCER | activates | gene | 0.60 |
| YAP | activates | gene | 0.60 |
| LATS1 | activates | gene | 0.60 |
| HIPPO | activates | gene | 0.60 |
| Oxidative Stress | activates | pathway | 0.60 |
| MST1 | activates | gene | 0.60 |
| Hippo Pathway | activates | pathway | 0.60 |
| HDAC6 | activates | gene | 0.60 |
| TAZ | activates | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| AND | activates | gene | 0.60 |
| OXIDATIVE STRESS | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MOB1 in their description or question text
No additional research found