gene 2,621 words KG: MERTK
Contents

MERTK - MER Tyrosine Kinase

🧬 Gene Info
Gene SymbolMERTK
Full NameMERTK - MER Tyrosine Kinase
AliasesPage for MERTK Protein
Chromosome2q14.1
Protein TypeGene
Primary Expressionmacrophages, microglia, photoreceptor cells, and neurons, where it mediates the clearance of apoptotic cells and cellular debris through recognition o
Molecular Weight110 kDa
Amino Acids998 aa
Exons20
PathwaysNF-κB, PI3K, MAPK
UniProt IDQ12866
NCBI Gene ID10488
Ensembl IDENSG00000153208
GeneCardsMERTK
Human Protein AtlasMERTK
Associated DiseasesAging, Alzheimer, Diabetes, Fibrosis, Hepatitis, Infection
InteractionsADAM8, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, Amyloid-Beta
KG Connections249 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

H4: Senomorphic Compounds Preserve Astrocyte Function While
Score: 0.71
TAM Receptor (MERTK/AXL) Cross-Regulation
Score: 0.54

Knowledge Graph (12 edges)

STAT6 expressed_in MERTK
EPHA4 expressed_in MERTK
MTOR activates MERTK
MERTK activates AKT
MERTK activates MAF
MERTK expressed_in GFAP
MERTK expressed_in ALDH1L1
MERTK expressed_in STAT6
MERTK expressed_in EPHA4
BAX activates MERTK

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