mechanism 1,502 words KG: PSP
Contents

lipid-metabolism-psp

Mechanism Info
NamePSP
Key Genes/ProteinsABCA7, Actin, AGING, AKT, ALZHEIMER, ALZHEIMER DISEASE
Related DiseasesAging, Als, ALS, Alzheimer, Alzheimer's disease
Related PathwaysAkt, Amyloid

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Related Hypotheses (107)

TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68
Osmotic Gradient Restoration via Selective AQP1 Enhancement
Score: 0.68
Oligodendrocyte Protectin D1 Mimetic for Myelin Resolution
Score: 0.68
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.67
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Complement C1q Subtype Switching
Score: 0.66
RNA Granule Nucleation Site Modulation
Score: 0.66
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Oligodendrocyte White Matter Vulnerability
Score: 0.65
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
HCN1-Mediated Resonance Frequency Stabilization Therapy
Score: 0.65
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Ephrin-B2/EphB4 Axis Manipulation
Score: 0.64
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Related Analyses (11)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
CRISPR-based therapeutic approaches for neurodegenerative di
neurodegeneration · archived
Extracellular vesicle biomarkers for early AD detection
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived

Knowledge Graph (12 edges)

DUSP10 associated_with PSP
MAP1S associated_with PSP
PSP associated_with SP1
PSP associated_with APOE
PSP associated_with TAU
PSP associated_with KIF13A
PSP associated_with TRIM24
PSP associated_with STX6
PSP associated_with MAPT
TAU activates PSP

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