gene 2,068 words KG: YWHAH
Contents

YWHAH Gene — 14-3-3 Eta (η) Protein

🧬 Gene Info
Gene SymbolYWHAH
Full NameTyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta
Aliases14-3-3 Eta (η) Protein
Chromosome22q12.3
FunctionPhosphorylation: Affects target protein binding affinity
Primary Expressionall eukaryotic cells[@yau2015]
Molecular Weight28 kDa
Amino Acids246 aa
Exons6
UniProt IDQ9Y2H5
NCBI Gene ID7535
Ensembl IDENSG00000128245
OMIM608456
GeneCardsYWHAH
Human Protein AtlasYWHAH
Associated Diseasesneurodegeneration
InteractionsAND, CANCER, circEHD2, CYTOKINES, FUS, HNRNPA2B1
KG Connections25 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Axonal RNA Transport Reconstitution
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (7)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
FUS (Redirect)
redirect · KG edge: activates
CBL Gene
gene · KG edge: associated_with
CRKL Gene
gene · KG edge: associated_with
DOCK1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

NDUFA2 associated_with YWHAH
NDUFS6 associated_with YWHAH
NDUFA1 associated_with YWHAH
CBL associated_with YWHAH
PDGFRB associated_with YWHAH
HSP90AB1 associated_with YWHAH
CRKL associated_with YWHAH
DOCK1 associated_with YWHAH
NDUFA12 associated_with YWHAH
YWHAH associated_with NDUFS5

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