gene 2,503 words KG: DOCK1
Contents

DOCK1 Gene

🧬 Gene Info
Gene SymbolDOCK1
Full NameDedicator of Cytokinesis 1
Chromosome10q26.3
Functionis a member of the DOCK family of guanine nucleotide exchange factors (GEFs) that specifically activate Rho GTPases, particularly Rac1.
Primary ExpressionBrain, Heart, Liver, Lung, Kidney
Molecular Weight210 kDa
Amino Acids1864 aa
Exons35
UniProt IDQ8IU85
NCBI Gene ID1791
Ensembl IDENSG00000123146
OMIM606003
GeneCardsDOCK1
Human Protein AtlasDOCK1
Associated DiseasesAlzheimer's disease, Parkinson's disease
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68
Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.68

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Neurodegeneration
disease · KG edge: implicated_in
CBL Gene
gene · KG edge: associated_with
CRKL Gene
gene · KG edge: associated_with
HSP90AB1 Gene
gene · KG edge: associated_with
NDUFA1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

NDUFA2 associated_with DOCK1
NDUFS6 associated_with DOCK1
NDUFA1 associated_with DOCK1
CBL associated_with DOCK1
PDGFRB associated_with DOCK1
HSP90AB1 associated_with DOCK1
CRKL associated_with DOCK1
DOCK1 associated_with NDUFA12
DOCK1 associated_with YWHAH
DOCK1 associated_with NDUFS5

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)