gene 1,383 words KG: CRKL
Contents

CRKL Gene

🧬 Gene Info
Gene SymbolCRKL
AliasesCRK-like proto-oncogene
Chromosome22q11.21
Protein TypeAdaptor Protein
Functionis a gene encoding an adaptor protein that plays critical roles in intracellular signal transduction.
Subcellular LocalizationCytoplasm, plasma membrane
Molecular Weight34 kDa
Amino Acids303 aa
Exons12
PathwaysMAPK pathway
UniProt IDP46109
NCBI Gene ID1399
GeneCardsCRKL
Human Protein AtlasCRKL
Associated Diseasesneurodegeneration
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Neurodegeneration
disease · KG edge: implicated_in
CBL Gene
gene · KG edge: associated_with
DOCK1 Gene
gene · KG edge: associated_with
HSP90AB1 Gene
gene · KG edge: associated_with
NDUFA1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

NDUFA2 associated_with CRKL
NDUFS6 associated_with CRKL
NDUFA1 associated_with CRKL
CBL associated_with CRKL
PDGFRB associated_with CRKL
HSP90AB1 associated_with CRKL
CRKL associated_with DOCK1
CRKL associated_with NDUFA12
CRKL associated_with YWHAH
CRKL associated_with NDUFS5

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