gene 566 words KG: WIF1
Contents

WIF1 Gene - Wnt Inhibitory Factor

🧬 Gene Info
Gene SymbolWIF1
AliasesPage for WIF1 Gene, Page for WIF1 Protein
Chromosome12q14.3
FunctionWIF1 is a key regulator of the Wnt/β-catenin signaling pathway
Primary ExpressionBrain, Eye, Lung, Testis, Cartilage
Molecular Weight36.5 kDa
PathwaysWnt, Wnt signaling, Wnt Signaling, Wnt pathway
UniProt IDQ9Y5W5
NCBI Gene ID11197
Ensembl IDENSG00000156076
OMIM605326
GeneCardsWIF1
Human Protein AtlasWIF1
Associated DiseasesCancer, Lung Cancer, neurodegeneration, Tumor, Visual Function
InteractionsALZHEIMER, ALZHEIMER'S DISEASE, AMPK, AMYLOID, AUTOPHAGY, AXIN2
KG Connections111 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.95
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (10)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: inhibits
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: inhibits
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
Genes
index · KG edge: inhibits
BECN1 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

WIF1 inhibits NPTX2
WIF1 associated_with MET
NPTX2 inhibits WIF1
WIF1 therapeutic_target DISC1
MET associated_with WIF1
WIF1 inhibits TAU
TAU inhibits WIF1
WIF1 regulates Wnt Signaling
WIF1 regulates GSK3B
BECN1 activates WIF1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)