| Gene Symbol | VGLUT2 |
| Aliases | Vesicular Glutamate Transporter 2 |
| Chromosome | 19q13.43 |
| Protein Type | Gene |
| Function | Its function encompasses several critical processes |
| Primary Expression | hypothalamic nuclei controlling autonomic and endocrine functions - Cortex: Limited to deep layers (V-VI) and specific interneuron populations - |
| Molecular Weight | 65 kDa |
| Amino Acids | 582 aa |
| Pathways | Epigenetic, Synaptic Plasticity, Synaptic Vesicle |
| GeneCards | VGLUT2 |
| Human Protein Atlas | VGLUT2 |
| Thalamus | Highest expression across all thalamic relay nuclei, particularly the ventral posterolateral and ventral posteromedial nuclei[@schoch2016] |
| Brainstem | Abundant in the red nucleus, substantia nigra pars reticulata, superior colliculus, and pontine nuclei[@tondereau2008] |
| Spinal Cord | Prominent in dorsal horn neurons, especially laminae I-II involved in pain transmission[@shabel2014] |
| Hypothalamus | Expressed in hypothalamic nuclei controlling autonomic and endocrine functions |
| Associated Diseases | epilepsy, Ischemia, neurodegeneration |
| Interactions | 6-OHDA, AND, ANXIETY, CSF1R, EPILEPSY, ERK1 |
| KG Connections | 55 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!