gene 1,700 words KG: TNFR2
Contents

TNFRSF1B Gene

🧬 Gene Info
Gene SymbolTNFR2
AliasesTNFRSF1B Protein
Chromosome1p36.22
Protein TypeReceptor
Functionis a member of the tumor necrosis factor receptor superfamily.
Primary ExpressionUbiquitous
Molecular Weight75 kDa
Amino Acids461 aa
Exons10
PathwaysNF-κB, PI3K, MAPK
UniProt IDP20333
NCBI Gene ID7133
GeneCardsTNFR2
Human Protein AtlasTNFR2
Associated DiseasesAlzheimer, Inflammation, Ms, Neurodegeneration, Neuroinflammation, Parkinson
InteractionsAGING, ALS, ALZHEIMER, AMYOTROPHIC LATERAL SCLEROSIS, AND, APOPTOSIS
KG Connections181 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Multi-Modal Stress Response Harmonization
Score: 0.76
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Astrocytes
cell · KG edge: expressed_in
Amyotrophic Lateral Sclerosis
redirect · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
Astrocytes
entity · KG edge: expressed_in
GFAP (Redirect)
redirect · KG edge: regulates

Knowledge Graph (12 edges)

TNFR2 regulates SYNAPTIC_FUNCTION
TNFR2 regulates SYNAPTIC_PLASTICITY
TNF activates TNFR2
GFAP regulates TNFR2
TNF regulates TNFR2
TNFR2 expressed_in TNFR1
SOD2 associated_with TNFR2
CAT associated_with TNFR2
BAX associated_with TNFR2
SPR associated_with TNFR2

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