| Gene Symbol | SYNE2 |
| Full Name | Spectrin Repeat Containing Nuclear Envelope Protein 2 |
| Chromosome | 14q23.1 |
| Protein Type | Nuclear envelope protein (Nesprin family) |
| Function | is a multi-isofor protein generated by alternative splicing, with the giant isoform (nesprin-2 giant, ~800 kDa) being the most studied in the context of nuclear envelope integrity and mechanotransd... |
| Primary Expression | Heart, Skeletal muscle, Brain, Endothelium |
| Subcellular Localization | the nuclear envelope that forms the core component of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex. The |
| Molecular Weight | 800 kDa |
| Gene Type | Protein coding |
| UniProt ID | Q8WXR4 |
| NCBI Gene ID | 23224 |
| Ensembl ID | ENSG00000008952 |
| OMIM | 608687 |
| GeneCards | SYNE2 |
| Human Protein Atlas | SYNE2 |
| Associated Diseases | Als, Alzheimer |
| Interactions | ADRA2A, ALDH1A2, ALZHEIMER, APOE, APP, CALB1 |
| KG Connections | 80 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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