concept

ABCC8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ABCC8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections

0Hypotheses

0Analyses

18Outgoing

1Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ABCC8
Key Genes/Proteins	AQP1, BMPR1A, BMPR1B, KLF2, KLK1, NOTCH3

Pathway Diagram

graph TD
    ABCC8[ABCC8]
    ABCC8 -->|regulates| Blood_Flow_Regulation[Blood Flow Regulation]
    ABCC8 -->|modulates| blood_flow[blood flow]
    ABCC8 -->|expressed in| Pericyte[Pericyte]
    ABCC8 -->|regulates| SLC2A2[SLC2A2]
    ABCC8 -->|interacts| KLK1[KLK1]
    ABCC8 -->|interacts| PAH[PAH]
    ABCC8 -->|participates in| ubiquitin_proteasome[ubiquitin-proteasome]
    ABCC8 -->|participates in| TGF_beta_signaling[TGF-beta signaling]
    ABCC8 -->|interacts| KLF2[KLF2]
    benchmark_ot_ad_answer_key_ABC[benchmark_ot_ad_answer_key:ABCC8] -->|data_in| ABCC8

Outgoing (18)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ABCC8	data_in	dataset_row	0.00
Blood Flow Regulation	regulates	process	0.85
blood flow	modulates	process	0.85
Pericyte	expressed_in	cell_type	0.80
BMPR1A	associated_with	gene	0.60
BMPR1B	associated_with	gene	0.60
NOTCH3	associated_with	gene	0.60
SMAD1	associated_with	gene	0.60
SMAD4	associated_with	gene	0.60
TET2	associated_with	gene	0.60
KLK1	interacts_with	gene	0.60
PAH	interacts_with	gene	0.60
ubiquitin-proteasome	participates_in	pathway	0.60
AQP1	associated_with	gene	0.60
SLC2A2	regulates	gene	0.60
SLC2A2	interacts_with	gene	0.60
TGF-beta signaling	participates_in	pathway	0.60
KLF2	interacts_with	gene	0.60

Incoming (1)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ABCC8	data_in	dataset_row	0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ABCC8 in their description or question text

No additional research found