gene 2,463 words KG: SLC17A9
Contents

SLC17A9 Gene

🧬 Gene Info
Gene SymbolSLC17A9
Full NameSolute Carrier Family 17 Member 9
Chromosome17q21.32
Protein TypeTransporter
Functionis a critical transmembrane protein responsible for the storage and release of nucleotides, particularly adenosine triphosphate (ATP), from secretory vesicles.
Molecular Weight52 kDa
Amino Acids477 aa
Exons14
PathwaysInflammasome
UniProt IDQ9NRH3 (SLC9A_HUMAN)
NCBI Gene ID131670
Ensembl IDENSG00000139233
GeneCardsSLC17A9
Human Protein AtlasSLC17A9
Associated Diseasesneurodegeneration
InteractionsCytokine, IL-1, INFLAMMATION, Interleukin, P2X7, Ras
KG Connections29 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (13)

Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77
Epigenetic Memory Erasure via TET2 Activation
Score: 0.74
Purinergic Signaling Polarization Control
Score: 0.71
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.71
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
Microbial Inflammasome Priming Prevention
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.70
Microglial Purinergic Reprogramming
Score: 0.70
Gap Junction Hemichannel Modulation for Controlled Mitochond
Score: 0.36

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

Related Experiments (5)

Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT
validation · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40
Mechanism: Progranulin Loss and TDP-43 Pathology in FTD
validation · proposed · Score: 0.40
TDP-43 PET Ligand Development for FTD and ALS
clinical · proposed · Score: 0.40

See Also (5)

ATP P2X3 Receptor Neurons
cell · KG edge: associated_with
P2RX7 Gene
gene · KG edge: associated_with
Purinergic Receptor P2X 7 (P2X7)
gene · KG edge: activates
NLRP3 Inflammasome Hypothesis in Parkinson's Disease
hypothesis · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: activates

Knowledge Graph (12 edges)

P2RX7 associated_with SLC17A9
SLC17A9 associated_with NLRP3
SLC17A9 activates P2X7
P2X7 activates SLC17A9
NLRP3 associated_with SLC17A9
SLC17A9 associated_with P2RX7
NLRP3 transports SLC17A9
SLC17A9 transports P2RX7
NLRP3 co_mentioned SLC17A9
P2RX7 co_mentioned SLC17A9

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