gene 578 words KG: RGS2
Contents

RGS2 Gene - Regulator of G Protein Signaling 2

🧬 Gene Info
Gene SymbolRGS2
Full NameRegulator of G Protein Signaling 2
AliasesPage for RGS2 Gene, Page for RGS2 Protein
Chromosome1q31.3
FunctionRGS2 is a key negative regulator of G protein signaling
Primary Expressionmany tissues:
Molecular Weight24 kDa
UniProt IDP41221
NCBI Gene ID5997
Ensembl IDENSG00000147251
OMIM600861
GeneCardsRGS2
Human Protein AtlasRGS2
Associated Diseasesneurodegeneration
InteractionsARHGEF7, AUTOPHAGY, CDC42, LRRK2, MAPK, PARKINSON
KG Connections25 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

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Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.98
Purinergic Signaling Polarization Control
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (8)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Parkinson Basal Ganglia Circuit
circuit · KG edge: interacts_with
Neurodegeneration
disease · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: interacts_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
ARHGEF7 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

RAB7L1 interacts_with RGS2
ARHGEF7 interacts_with RGS2
RAC1 interacts_with RGS2
LRRK2 interacts_with RGS2
RGS2 interacts_with CDC42
RGS2 interacts_with RAB5
CDC42 interacts_with RGS2
RGS2 interacts_with ARHGEF7
DDB1 regulates RGS2
RGS2 regulates FHL1

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