| Gene Symbol | RAB7 |
| Full Name | Member RAS Oncogene Family |
| Aliases | RAB7, member RAS oncogene family |
| Function | RAB7 is a master regulator of late endosomal/lysosomal trafficking: - Late endosome maturation: Regulates transition from early to late endosomes - Lysosomal fusion: Controls SNARE-mediated fusion wit |
| Molecular Weight | 23 kDa |
| Amino Acids | 207 aa |
| Exons | 7 |
| Pathways | PI3K |
| GeneCards | RAB7 |
| Human Protein Atlas | RAB7 |
| GTPase-activating proteins (GAPs) | Accelerate GTP hydrolysis (e.g., TBC1D5, TBC1D15) |
| GDP dissociation inhibitors (GDIs) | Extract GDP-bound RAB7 from membranes for recycling |
| Associated Diseases | Als, Ataxia, disease, Neurodegeneration |
| Interactions | ALZHEIMER'S DISEASE, AMYLOID, AND, ATP6V1G1, AUTOPHAGY, CCT5 |
| KG Connections | 218 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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