| Gene Symbol | PON1 |
| Chromosome | 7q21.3. |
| Protein Type | Enzyme |
| Function | is a calcium-dependent esterase enzyme encoded by the PON1 gene on chromosome 7q21. |
| Primary Expression | the liver (hepatocytes) and secreted into plasma |
| Molecular Weight | 43 kDa |
| Amino Acids | 354 aa |
| UniProt ID | P27169 |
| NCBI Gene ID | 5444 |
| Ensembl ID | ENSG00000005421 |
| OMIM | 168000 |
| GeneCards | PON1 |
| Human Protein Atlas | PON1 |
| LDL protection | Prevents copper-catalyzed oxidation of low-density lipoprotein |
| HDL association | Tightly bound to apoA-I on HDL particles |
| Associated Diseases | Als, Atherosclerosis, Breast Cancer, Cancer, Depression, Inflammation |
| Interactions | CLU |
| KG Connections | 46 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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