| Gene Symbol | NUP98 |
| Full Name | Nucleoporin 98 |
| Chromosome | 11p15.4 |
| Function | peripheral localization: NUP98 contributes to both the central channel barrier and cytoplasmic filament-associated gating |
| Primary Expression | neurons throughout the central nervous system, with enrichment in the hippocampus, [prefrontal cort |
| Molecular Weight | 40 kDa |
| Amino Acids | 1817 aa |
| Pathways | ubiquitin-proteasome |
| UniProt ID | P52948 |
| NCBI Gene ID | 4928 |
| Ensembl ID | ENSG00000110713 |
| OMIM | 601021 |
| GeneCards | NUP98 |
| Human Protein Atlas | NUP98 |
| FG-hydrogel formation | The GLFG-repeat domain self-assembles into a cohesive hydrogel that fills the central channel, excluding macromolecules larger than ~40 kDa unless chaperoned by transport receptors |
| Associated Diseases | Alzheimer's Disease, Huntington's Disease |
| Known Drugs/Compounds | (S)-ACE-OH |
| Interactions | ACE, AND, CANCER, FLT3, NEURODEGENERATION, Proteins |
| SciDEX Hypotheses | C9orf72 Hexanucleotide Repeat Dipeptide Repeat Pro |
| KG Connections | 27 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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