gene 723 words KG: NCOR1
Contents

NCOR1 Gene - Nuclear Receptor Corepressor 1

🧬 Gene Info
Gene SymbolNCOR1
Full NameNuclear Receptor Corepressor 1
AliasesPage for NCOR1 Gene
Chromosome17p12
FunctionNCOR1 is a component of several corepressor complexes that regulate gene expression through chromatin remodeling
Primary ExpressionBrain (high), particularly cortex and hippocampus
Amino Acids440 aa
Exons24
PathwaysOxidative Stress, Proteasome
UniProt IDO75376
NCBI Gene ID9612
Ensembl IDENSG00000140989
OMIM607079
GeneCardsNCOR1
Human Protein AtlasNCOR1
Associated DiseasesCancer
InteractionsAND, App, BDNF, CCL2, COX2, HMGB1
KG Connections58 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (9)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.78
Multi-Modal Stress Response Harmonization
Score: 0.76
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
HDAC3-Selective Inhibition for Clock Reset
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67

Related Analyses (6)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed

See Also (13)

Apoptosis in Neurodegeneration
entity · KG edge: therapeutic_target
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
ARNT2 - Aryl Hydrocarbon Receptor Nuclear Translocator
gene · KG edge: transports
ATRX — Alpha Thalassemia/Mental Retardation Syndrome X-
gene · KG edge: associated_with
BACH1 — BTB Domain and CNC Homolog 1
gene · KG edge: associated_with

Knowledge Graph (12 edges)

SIRT1 activates NCOR1
NCOR1 activates SIRT1
PPAR activates NCOR1
NCOR1 activates RNF20
NCOR1 activates UBIQUITIN
NCOR1 activates ITGA3
NCOR1 activates SGK1
NCOR1 activates BDNF
NCOR1 regulates Jnk
NR4A2 activates NCOR1

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