gene 1,271 words KG: MST1
Contents

MST1 Gene

🧬 Gene Info
Gene SymbolMST1
Chromosome19p13.3
Protein TypeSerine/Threonine Kinase
Functionencodes a serine/threonine kinase that belongs to the Hippo signaling pathway.
Primary Expressionvarious tissues:
Molecular Weight56 kDa
Amino Acids487 aa
PathwaysPI3K, MAPK pathway
UniProt IDQ13043
NCBI Gene ID6789
Ensembl IDENSG00000101189
OMIM604995
GeneCardsMST1
Human Protein AtlasMST1
Associated DiseasesAlzheimer's disease, Ms
InteractionsAND, CANCER, CGAS, CGAS-STING, DYRK1A, GATA2
KG Connections150 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.76
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Aquaporin-4 Polarization Rescue
Score: 0.73
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived

See Also (11)

ATP P2X3 Receptor Neurons
cell · KG edge: regulates
Apoptosis in Neurodegeneration
entity · KG edge: regulates
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: regulates
AQP4 (Aquaporin-4 Gene)
gene · KG edge: expressed_in
GATA2 - GATA Binding Protein 2
gene · KG edge: activates

Knowledge Graph (12 edges)

MST1 activates LATS1
MST1 interacts_with PGC1α
MST1 regulates mitochondrial homeostasis
MST1 activates neuronal apoptosis
MST1 activates cognitive decline
MST1 activates cognitive impairment
STING activates MST1
MST1 activates CGAS
PI3K regulates MST1
AKT regulates MST1

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