concept

NEURONAL APOPTOSIS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NEURONAL APOPTOSIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

68Connections

1Hypotheses

0Analyses

1Outgoing

50Incoming

0Experiments

0Debates

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💡 Concept Info

Name	NEURONAL APOPTOSIS

Pathway Diagram

graph TD
    NEURONAL_APOPTOSIS["NEURONAL APOPTOSIS"]
    ASK1["ASK1"] -->|"regulates"| NEURONAL_APOPTOSIS
    Yiqi_Tongluo_Granule["Yiqi Tongluo Granule"] -->|"inhibits"| NEURONAL_APOPTOSIS
    Cordycepin["Cordycepin"] -->|"inhibits"| NEURONAL_APOPTOSIS
    Caspase_3["Caspase-3"] -->|"promotes"| NEURONAL_APOPTOSIS
    DLK_Inhibition["DLK Inhibition"] -->|"inhibits"| NEURONAL_APOPTOSIS
    Bergenin["Bergenin"] -->|"inhibits"| NEURONAL_APOPTOSIS
    C3_C3aR_Pathway["C3/C3aR Pathway"] -->|"activates"| NEURONAL_APOPTOSIS

Outgoing (1)

Target	Relation	Type	Str
Cognitive Deficits	causes	phenotype	0.85

Incoming (67)

Source	Relation	Type	Str
BDNF	protects_against	protein	0.95
ASK1	activates	protein	0.95
ASK1	regulates	protein	0.95
ACTG1	promotes	protein	0.90
Unfolded Protein Response	mediates	pathway	0.90
TAZ	suppresses	gene	0.90
Aucubin	suppresses	compound	0.90
Ceramide	promotes	compound	0.90
DLK Inhibition	inhibits	mechanism	0.90
Bergenin	inhibits	compound	0.90
TP53	activates	protein	0.90
Yiqi Tongluo Granule	inhibits	drug	0.90
PGAM5	promotes	protein	0.90
ZFP36	inhibits	gene	0.90
ER Stress	contributes_to	process	0.90
XYS	inhibits	compound	0.90
Brain Cholesterol Accumulation	promotes	phenotype	0.90
Cordycepin	inhibits	compound	0.90
mitochondrial dysfunction	promotes	phenotype	0.90
Caspase-3	promotes	protein	0.90
mitochondrial dysfunction	drives	phenotype	0.88
Bergenin	protects_against	compound	0.88
C3/C3aR Pathway	activates	pathway	0.88
TLR2	promotes	gene	0.88
Tong-Qiao-Huo-Xue Decoction	inhibits	drug	0.87
Ceramide	causes	compound	0.85
Myriocin	regulates	drug	0.85
Chronic Demyelination	causes	disease	0.85
Complement C3/C3Ar Pathway	mediates	pathway	0.85
mitochondrial transfer	protects_against	process	0.85
L-glutamate	drives	compound	0.85
TLR2	promotes	gene	0.85
Aucubin	suppresses	compound	0.85
ACTG1	promotes	protein	0.85
ceramide	promotes	compound	0.85
AMYLOID BETA	causes	protein	0.85
PI3K-Akt Signaling Pathway	modulates	pathway	0.85
ERK	inhibits	protein	0.80
TUFM	promotes	gene	0.80
Honokiol	inhibits	compound	0.80
BDNF	inhibits	gene	0.80
CLU	modulates	protein	0.80
Steroid Hormones	regulates	compound	0.80
WDR45	causes	gene	0.80
Pyroptosis	associated_with	process	0.80
PROBDNF	promotes	protein	0.80
BDNF	inhibits	gene	0.80
Steroid Hormones	inhibits	compound	0.72
MST1	activates	protein	0.70
Tryptophan metabolites	inhibits	drug	0.70

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
Colonic Th17/IL-17A Axis → Peripheral Immune Recruitment to	0.640	neurodegeneration	What are the mechanisms by which gut mic

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NEURONAL APOPTOSIS in their description or question text

No additional research found