| Gene Symbol | LATS2 |
| Full Name | Large Tumor Suppressor Kinase 2 |
| Chromosome | 13q12.11 |
| Protein Type | Serine/Threonine Kinase |
| Primary Expression | neural progenitor cells of the ventricular and subventricular zones, where it cooperates with LATS1 to restrict progenitor proliferati |
| Amino Acids | 1088 aa |
| Exons | 9 |
| Pathways | NF-κB |
| Ensembl ID | ENSG00000150457 |
| GeneCards | LATS2 |
| Human Protein Atlas | LATS2 |
| p53 stabilization | LATS2 inhibits MDM2 E3 ubiquitin ligase activity, stabilizing p53 in response to DNA damage and mitotic stress |
| Centrosome regulation | LATS2 localizes to centrosomes during mitosis and regulates centrosome duplication and mitotic fidelity |
| Associated Diseases | Breast Cancer |
| Interactions | AND, APOPTOSIS, CANCER, ESR1, HIPPO, LATS1 |
| KG Connections | 41 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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