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gene 1,671 words KG: KCNMA1
Contents

KCNMA1 Gene

🧬 Gene Info
Gene SymbolKCNMA1
Full NamePotassium Calcium-Activated Channel Subfamily M Alpha 1
AliasesBK channel, SLO1, KCa1.1
Chromosome10q22.3
FunctionLarge-conductance calcium-activated potassium channel (BK channel)
Molecular Weight126.0 kDa
Amino Acids1113
Exons28 exons spanning the coding sequence
PathwaysPotassium transport, Neuronal excitability
UniProt IDQ12791
Ensembl IDENSG00000156113
GeneCardsKCNMA1
Human Protein AtlasKCNMA1
Genomic Size~160 kb
Alternative SplicingMultiple splice variants generate channel diversity [1]
Associated DiseasesCancer
KG Connections103 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (3)

Mechanosensitive Ion Channel Reprogramming
Score: 0.70Extracellular Matrix Stiffness Modulation
Score: 0.69Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67

Related Analyses (3)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedPerivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (6)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40Anti-Tau Antibody vs ASO/Gene Therapy — Comparative Efficacy
validation · proposed · Score: 0.40cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40

See Also (8)

blarcamesine-axon
clinical_trial · KG edge: associated_withGenes
index · KG edge: causesCACNA1B Gene
gene · KG edge: associated_withCACNA1C Gene
gene · KG edge: associated_withCFTR Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PIEZO1 associated_with KCNMA1
KCNK2 associated_with KCNMA1
SCN5A associated_with KCNMA1
TRPM7 associated_with KCNMA1
SCN1A associated_with KCNMA1
TRPV4 associated_with KCNMA1
CACNA1B associated_with KCNMA1
SCNN1A associated_with KCNMA1
CFTR associated_with KCNMA1
PIEZO2 associated_with KCNMA1

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