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gene 679 words KG: GSS
Contents

GSS Gene

🧬 Gene Info
Gene SymbolGSS
Full NameGlutathione Synthetase
AliasesGSH-S
Chromosome20q11.22
FunctionCatalyzes second step of glutathione biosynthesis
Molecular Weight52.4 kDa
Amino Acids474
PathwaysGlutathione biosynthesis, Oxidative stress defense
UniProt IDP48637
Ensembl IDENSG00000100983
GeneCardsGSS
Human Protein AtlasGSS
Associated DiseasesAD, AMI, ARM, cancer, disease, Ms
InteractionsACSL5, AND, ASTROCYTE, ASTROCYTES, CANCER, CYP2E1
KG Connections83 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.92Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (5)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Pre-Symptomatic Detection and Intervention Timing in Genetic
validation · proposed · Score: 0.40

See Also (8)

Astrocytes
entity · KG edge: activatesastrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: activatesGenes
index · KG edge: co_discussedAPP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: therapeutic_targetAccelerating Medicines Partnership for Alzheimer's Dise
institution · KG edge: implicated_in

Knowledge Graph (12 edges)

JUN therapeutic_target GSS
SLC16A2 therapeutic_target GSS
GSS implicated_in AD
GSS implicated_in AMI
GSS implicated_in ARM
GSS implicated_in RA
GSS implicated_in SS
GSS implicated_in disease
GSS activates JUN
GSS activates SLC16A2

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