| Gene Symbol | FKBP1A |
| Full Name | FKBP Prolyl Isomerase 1A |
| Chromosome | 20p13 |
| Protein Type | Isomerase |
| Function | FKBP1A encodes a member of the FK506-binding protein family of peptidyl-prolyl cis-trans isomerases (PPIases). |
| Primary Expression | neurons and glia, with particularly high expression in regions involved in learning and memory |
| Subcellular Localization | the cytoplasm and performs several key cellular functions[@fkbp2012]: |
| Amino Acids | 108 aa |
| Pathways | mTOR, mtor |
| UniProt ID | [P62942](https://www.uniprot.org/uniprot/P62942) |
| Ensembl ID | ENSG00000107164 |
| GeneCards | FKBP1A |
| Human Protein Atlas | FKBP1A |
| PPIase activity | Catalyzes the cis-trans isomerization of peptide bonds preceding proline residues, accelerating protein folding |
| Chaperone function | Assists in proper protein folding and prevents aggregation of misfolded proteins |
| Associated Diseases | Huntington |
| Known Drugs/Compounds | rapamycin |
| Interactions | AGING, AUTOPHAGY, FKBP5, HTT, HUNTINGTIN, HUNTINGTON |
| KG Connections | 38 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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