| Gene Symbol | EFNB2 |
| Full Name | Ephrin B2 |
| Protein Type | Receptor |
| Function | is a transmembrane ligand for the Eph family of receptor tyrosine kinases. |
| Molecular Weight | 38 kDa |
| Amino Acids | 333 aa |
| Pathways | Cerebrovascular Development |
| Ensembl ID | ENSG00000145088 |
| GeneCards | EFNB2 |
| Human Protein Atlas | EFNB2 |
| Ephrin A ligands (EFNA1-5) | GPI-anchored |
| Ephrin B ligands (EFNB1-3) | transmembrane |
| Receptor-binding domain | interacts with Eph receptors |
| Conserved cysteine-rich region | maintains structural integrity |
| Cleavage site | can be proteolytically processed |
| Associated Diseases | Congenital Cerebrovascular Disease, Vein Of Galen Malformation |
| Known Drugs/Compounds | Icariin |
| Interactions | EPHB4, GFAP, GRB2, NFKB1 |
| KG Connections | 28 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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