gene 1,385 words KG: CNR2
Contents

CNR2 Gene - Cannabinoid Receptor 2 (CB2)

🧬 Gene Info
Gene SymbolCNR2
Full NameCannabinoid Receptor Type 2
Chromosome1p36.12
Functionis a component of the endocannabinoid system, a neuromodulatory system involved in various physiological processes including pain sensation, immune response, and neuroinflammation.
Primary Expressionimmune cells and peripheral tissues
Molecular Weight40 kDa
Amino Acids360 aa
PathwaysMAPK pathway, PI3K
UniProt IDP47972
NCBI Gene ID1269
Ensembl IDENSG00000188322
OMIM605026
GeneCardsCNR2
Human Protein AtlasCNR2
7 transmembrane domainsOrganized as a typical GPCR barrel
Associated DiseasesALS, Alzheimer
Interactionsadcy2, ADCY2, ALZHEIMER, ALZHEIMER'S DISEASE, C3AR1, CCR5
KG Connections47 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (1)

Circadian Glymphatic Rescue Therapy (Melatonin-focused)
Score: 0.71

Related Analyses (2)

Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

CB2R deletion effects on GVHD-induced behavioral changes
validation · proposed · Score: 0.90
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs
clinical · proposed · Score: 0.90
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40

See Also (9)

ADCY2 — Adenylate Cyclase 2
gene · KG edge: associated_with
C3AR1 Gene
gene · KG edge: associated_with
CCR5 Gene
gene · KG edge: associated_with
CXCL12 Gene
gene · KG edge: associated_with
cxcl8
gene · KG edge: associated_with

Knowledge Graph (12 edges)

APP expressed_in CNR2
TAU activates CNR2
CXCL12 associated_with CNR2
ADCY2 associated_with CNR2
GRM2 associated_with CNR2
NPY associated_with CNR2
CXCL8 associated_with CNR2
CCR5 associated_with CNR2
MTNR1A associated_with CNR2
CNR2 associated_with C3AR1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)