gene 1,802 words KG: CAPZB
Contents

CAPZB Gene

🧬 Gene Info
Gene SymbolCAPZB
Full NameCapping Actin Protein of the Z-disc Beta
Chromosome1p36.22
FunctionThis binding prevents the addition or loss of actin subunits at this end, functioning through several mechanisms
Primary Expressionthe brain with specific patterns:
Molecular Weight31 kDa
UniProt IDP47756
NCBI Gene ID832
Ensembl IDENSG00000015590
OMIM601568
GeneCardsCAPZB
Human Protein AtlasCAPZB
Associated DiseasesAls, Alzheimer
Known Drugs/Compoundsaducanumab
InteractionsCD81, GDI2, NDUFA4, NDUFS7, NEURODEGENERATIVE DISEASES, PLCB1
KG Connections46 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Lysosomal Enzyme Trafficking Correction
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67

Related Analyses (4)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: associated_with
Mitochondria
entity · KG edge: regulates
CANX — Calnexin
gene · KG edge: therapeutic_target
CD81
gene · KG edge: regulates
GDI2 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

RAB7A therapeutic_target CAPZB
IGF2R therapeutic_target CAPZB
CAPZB therapeutic_target RAB5A
CAPZB therapeutic_target HSPA1A
CAPZB therapeutic_target RAB8A
CAPZB therapeutic_target CANX
CAPZB therapeutic_target HSPA5
CD81 regulates CAPZB
GDI2 regulates CAPZB
MAG regulates CAPZB

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