gene

NDUFS7

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NDUFS7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

37Connections

0Hypotheses

0Analyses

20Outgoing

17Incoming

0Experiments

0Debates

Summary

NDUFS7 Gene

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🧬 Gene Info

Gene Symbol	NDUFS7
Function	The NDUFS7 gene encodes NDUFS7 Protein, a protein involved in various cellular processes relevant to neuronal function and survival.
Primary Expression	various brain regions, with notable expression in: - Cerebral cortex - Hippocampus - Basal gang
Pathways	Amyloid
Ensembl ID	ENSG00000115286
GeneCards	NDUFS7
Human Protein Atlas	NDUFS7
Associated Diseases	Als, Alzheimer
Known Drugs/Compounds	aducanumab
Interactions	CAPZB, CD81, GDI2, NDUFA4, PLCB1, Proteins
KG Connections	37 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

NDUFS7 Gene

gene · 604 words

→

NDUFS7 Protein

protein · 1090 words

→

Pathway Diagram

graph TD
    NDUFS7["NDUFS7"]
    Alzheimer["Alzheimer"]
    NDUFS7 -->|"associated with"| Alzheimer
    Als["Als"]
    NDUFS7 -->|"associated with"| Als
    ALS["ALS"]
    NDUFS7 -->|"associated with"| ALS
    CAPZB["CAPZB"]
    NDUFS7 -->|"regulates"| CAPZB
    NDUFA4["NDUFA4"]
    NDUFS7 -->|"regulates"| NDUFA4
    MITOCHONDRIA["MITOCHONDRIA"]
    NDUFS7 -->|"regulates"| MITOCHONDRIA
    AND["AND"]
    NDUFS7 -->|"regulates"| AND
    MAG["MAG"]
    NDUFS7 -->|"regulates"| MAG
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    NDUFS7 -->|"associated with"| ALZHEIMER_S_DISEASE
    AMYLOID["AMYLOID"]
    NDUFS7 -->|"associated with"| AMYLOID
    PLCB1["PLCB1"]
    NDUFS7 -->|"regulates"| PLCB1
    CD81["CD81"]
    NDUFS7 -->|"regulates"| CD81
    Amyloid["Amyloid"]
    NDUFS7 -->|"associated with"| Amyloid
    MITOCHONDRIA["MITOCHONDRIA"]
    MITOCHONDRIA -->|"regulates"| NDUFS7
    CD81["CD81"]
    CD81 -->|"regulates"| NDUFS7
    GDI2["GDI2"]
    GDI2 -->|"regulates"| NDUFS7
    MAG["MAG"]
    MAG -->|"regulates"| NDUFS7
    HK1["HK1"]
    HK1 -->|"regulates"| NDUFS7
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"associated with"| NDUFS7
    PLCB1["PLCB1"]
    PLCB1 -->|"regulates"| NDUFS7
    CAPZB["CAPZB"]
    CAPZB -->|"regulates"| NDUFS7
    neurodegeneration["neurodegeneration"]
    NDUFS7 -->|"implicated in"| neurodegeneration

Outgoing (20)

Target	Relation	Type	Str
ALS	associated_with	disease	0.65
Alzheimer	associated_with	disease	0.65
Als	associated_with	disease	0.65
Raf	regulates	protein	0.60
App	associated_with	protein	0.60
AND	regulates	gene	0.60
ALZHEIMER'S DISEASE	associated_with	gene	0.60
AMYLOID	associated_with	gene	0.60
Amyloid	associated_with	pathway	0.60
CAPZB	regulates	gene	0.60
NDUFA4	regulates	gene	0.60
MAG	regulates	gene	0.60
PLCB1	regulates	gene	0.60
MITOCHONDRIA	regulates	gene	0.60
CD81	regulates	gene	0.60
HK1	regulates	gene	0.60
Aβ	regulates	protein	0.60
NDUFA4	interacts_with	gene	0.50
PLCB1	co_expressed_with	gene	0.50
Proteins	interacts_with	protein	0.50

Incoming (17)

Source	Relation	Type	Str
CD81	regulates	gene	0.60
GDI2	regulates	gene	0.60
MAG	regulates	gene	0.60
HK1	regulates	gene	0.60
PLCB1	regulates	gene	0.60
CAPZB	regulates	gene	0.60
MITOCHONDRIA	regulates	gene	0.60
ALZHEIMER	associated_with	gene	0.60
NDUFA4	regulates	gene	0.60
aducanumab	targets	drug	0.60
MITOCHONDRIA	interacts_with	cell_type	0.50
PLCB1	interacts_with	gene	0.50
CD81	interacts_with	gene	0.50
GDI2	interacts_with	gene	0.50
CAPZB	interacts_with	protein	0.50
MAG	co_expressed_with	gene	0.50
NDUFA4	co_expressed_with	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NDUFS7 in their description or question text

No additional research found