gene 672 words KG: AURKB
Contents

AURKB Gene

🧬 Gene Info
Gene SymbolAurora Kinase B
AliasesAURKB
Chromosome17p13.1
Functionis a chromosome passenger complex protein essential for mitosis and cytokinesis.
Subcellular Localization. The CPC, composed of Aurora B, survivin (BIRC5), INCENP, and Borealin, targets Aurora B to the inner centromere during
Gene TypeProtein Coding
UniProt IDQ96GD4
NCBI Gene ID9212
Ensembl IDENSG00000178999
Associated Diseasesneurodegeneration
Known Drugs/Compoundsrapamycin
InteractionsACTB, AMPK, ASPM, ATG, CALM1, CANCER
KG Connections85 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.90
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

Genes
index · KG edge: associated_with
CALM1 — Calmodulin 1
gene · KG edge: associated_with
CDC42 Gene
gene · KG edge: associated_with
GAP43 Gene
gene · KG edge: associated_with
KIF15 Gene - Kinesin Family Member 15
gene · KG edge: associated_with

Knowledge Graph (12 edges)

MYC activates AURKB
H2AX activates AURKB
AURKB activates MYC
CDC42 interacts_with AURKB
KIF15 associated_with AURKB
NEFL associated_with AURKB
AURKB associated_with TPR
AURKB therapeutic_target RANK
AURKB associated_with NEFH
AURKB interacts_with KIF5B

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