Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ASPM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | ASPM |
| Function | Aspm Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| Subcellular Localization | - **Phosphorylation sites** - cell cycle regulation The protein contains 81 pre |
| Molecular Weight | 347 kDa |
| GeneCards | ASPM |
| Human Protein Atlas | ASPM |
| Interactions | AURKB, CALM1 |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
ASPM["ASPM"]
ASPM -->|"interacts"| AURKB["AURKB"]
ASPM -->|"interacts"| CALM1["CALM1"]
ASPM ---|"associated"| KIF5B["KIF5B"]
ASPM ---|"associated"| Genes["Genes"]
ASPM ---|"co-discussed"| CDC42["CDC42"]
ASPM ---|"co-discussed"| GAP43["GAP43"]
GENES["GENES"] -->|"regulates"| ASPM
KIF15["KIF15"] ---|"associated"| ASPM
NEFL["NEFL"] ---|"associated"| ASPM
NEFH["NEFH"] ---|"associated"| ASPM
CDC42 ---|"associated"| ASPM
PVALB["PVALB"] ---|"associated"| ASPMHypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ASPM in their description or question text
No additional research found