concept

FZR1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FZR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

26Connections

0Hypotheses

0Analyses

20Outgoing

6Incoming

0Experiments

0Debates

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💡 Concept Info

Name	FZR1
Key Genes/Proteins	Actin, Anapc11, APC, App, CANCER, CDH1
Related Diseases	Als, ALS, Cancer
Related Pathways	Cell Cycle

Pathway Diagram

graph TD
    FZR1["FZR1"]
    FZR1 -->|"encodes"| CDH1["CDH1"]
    FZR1 -->|"activates"| Cancer["Cancer"]
    FZR1 -->|"activates"| ALS["ALS"]
    FZR1 -->|"activates"| Als["Als"]
    FZR1 -->|"activates"| UBIQUITIN["UBIQUITIN"]
    FZR1 -->|"activates"| JUN["JUN"]
    FZR1 -->|"activates"| AND["AND"]
    APC["APC"] -->|"activates"| FZR1
    DNA["DNA"] -->|"activates"| FZR1
    CDK2["CDK2"] -->|"activates"| FZR1
    UBIQUITIN -->|"activates"| FZR1
    CDH1 -->|"activates"| FZR1
    JUN -->|"activates"| FZR1

Outgoing (20)

Target	Relation	Type	Str
CDH1	encodes	protein	0.95
Anapc11	interacts_with	protein	0.85
ALS	activates	disease	0.65
Cancer	activates	disease	0.65
Als	activates	disease	0.65
CDK2	activates	gene	0.60
CANCER	activates	gene	0.60
Cell Cycle	activates	pathway	0.60
APC	activates	gene	0.60
JUN	activates	gene	0.60
CDH1	activates	gene	0.60
UBIQUITIN	activates	gene	0.60
T Cell	activates	cell_type	0.60
DNA	activates	gene	0.60
ubiquitin-proteasome	participates_in	pathway	0.60
Actin	activates	protein	0.60
Rb	activates	protein	0.60
Erk	activates	protein	0.60
App	activates	protein	0.60
T Cell	expressed_in	cell_type	0.55

Incoming (6)

Source	Relation	Type	Str
APC	activates	gene	0.60
DNA	activates	gene	0.60
CDK2	activates	gene	0.60
UBIQUITIN	activates	gene	0.60
CDH1	activates	gene	0.60
JUN	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FZR1 in their description or question text

No additional research found