gene 1,027 words KG: FZD7
Contents

FZD7 Gene

🧬 Gene Info
Gene SymbolFZD7
Full NameFrizzled Class Receptor 7
Chromosome2q33.3
Protein TypeReceptor
FunctionFZD7 (Frizzled Class Receptor 7) is a seven-transmembrane receptor belonging to the Frizzled family of Wnt receptors.
Primary Expressionneural stem cells and progenitor populations
UniProt IDO75084
NCBI Gene ID8324
Ensembl IDENSG00000155729
OMIM603410
GeneCardsFZD7
Human Protein AtlasFZD7
High affinity ligandsBinds Wnt1, Wnt2, Wnt3, and Wnt3A with high specificity
Stem cell pluripotencyMaintains embryonic stem cell self-renewal through β-catenin stabilization
Progenitor proliferationPromotes expansion of neural progenitor cells during development
Associated DiseasesAlzheimer's Disease, Cancer, Autism Spectrum Disorder
InteractionsWNT
KG Connections91 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

BRG1 therapeutic_target FZD7
NRCAM therapeutic_target FZD7
NOTCH2 therapeutic_target FZD7
EP300 therapeutic_target FZD7
CTNNB1 therapeutic_target FZD7
NEUROD1 therapeutic_target FZD7
MYC therapeutic_target FZD7
VEGFA therapeutic_target FZD7
FOXM1 therapeutic_target FZD7
LEF1 therapeutic_target FZD7

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