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entity 1,414 words KG: p62/SQSTM1
Contents

p62/SQSTM1 (Sequestosome-1)

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Wikipedia

Related Hypotheses (7)

APOE-Dependent Autophagy Restoration
Score: 0.88Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79Autophagosome Maturation Checkpoint Control
Score: 0.71VCP-Mediated Autophagy Enhancement
Score: 0.59Lysosomal Membrane Repair Enhancement
Score: 0.54PINK1/Parkin-Independent Mitophagy Bypass for Enhanced Donor
Score: 0.53Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48

Related Analyses (5)

APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archivedAutophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archivedWhat are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedMitochondrial transfer between neurons and glia
neurodegeneration · completed

Related Experiments (11)

iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · completed · Score: 0.90iPSC-NPC transplantation in ICH animal model
validation · proposed · Score: 0.85Autophagy receptor identification for stress granule elimina
exploratory · proposed · Score: 0.90Resveratrol protection against renal I/R injury in diabetic
validation · proposed · Score: 0.90Resveratrol effects on HK-2 cells under hypoxia/reoxygenatio
exploratory · proposed · Score: 0.85

See Also (13)

nf-kb
general · KG edge: regulatesAutophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: regulatesBRCA1 Gene
gene · KG edge: co_discussedDES Gene
gene · KG edge: co_discussedDNAJB6 Gene
gene · KG edge: associated_with

Knowledge Graph (11 edges)

LC3 interacts_with p62/SQSTM1
p62/SQSTM1 interacts_with LC3
p62/SQSTM1 regulates autophagy
NF-kB regulates p62/SQSTM1
p62/SQSTM1 binds LC3
NEMO co_localizes p62/SQSTM1
BAG3 interacts_with p62/SQSTM1
p62/SQSTM1 regulates selective autophagy
K63-ubiquitin chain activates p62/SQSTM1
p62/SQSTM1 activates autophagy pathway

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