entity

K63-ubiquitin chain

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about K63-ubiquitin chain: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

6Connections
0Hypotheses
1Analyses
4Outgoing
2Incoming
0Experiments
1Debates

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Outgoing (4)

TargetRelationTypeStr
p62/SQSTM1activatesprotein0.70
OPTNactivatesprotein0.70
autophagic receptor recruitmentmediatesprocess0.70
G3BP1 oligomerizationinhibitsprocess0.70

Incoming (2)

SourceRelationTypeStr
TRIM21catalyzesprotein0.90
DUBregulatesprotein0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

How does TRIM21-mediated K63 ubiquitination of G3BP1 mechanistically inhibit liq

neurodegeneration | 2026-04-07 | 7 hypotheses Top: 0.730

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (1)

Multi-agent debates referencing this entity

The study shows that G3BP1 ubiquitination inhibits LLPS in vitro, but the molecu

closed · Rounds: 4 · Score: 0.79 · 2026-04-21

Related Research

Hypotheses and analyses mentioning K63-ubiquitin chain in their description or question text

No additional research found