gene 1,755 words KG: DDB1
Contents

DDB1 — DNA Damage Binding Protein 1

🧬 Gene Info
Gene SymbolDDB1
Full NameDNA Damage Binding Protein 1
AliasesUV-DDB1, XPE-BF
Chromosome11q12.2
FunctionDNA damage recognition and repair, E3 ubiquitin ligase adapter
Molecular Weight126.9 kDa
Amino Acids1140
Exons22
PathwaysNucleotide excision repair, CUL4-DDB1 ubiquitin ligase
UniProt IDQ16531
Ensembl IDENSG00000167986
GeneCardsDDB1
Human Protein AtlasDDB1
CUL4A/CUL4BScaffold proteins that recruit the E2 conjugating enzyme
ROC1RING finger protein that activates E2 enzymes
Associated DiseasesCancer, Lung Cancer
Known Drugs/Compoundsrapamycin
InteractionsACTB, AGING, AMBRA1, AMPK, AND, ANG
KG Connections105 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

TAZ regulates DDB1
LATS1 regulates DDB1
TSC2 regulates DDB1
ATF4 regulates DDB1
TSC1 regulates DDB1
MTOR regulates DDB1
WIPI2 activates DDB1
DDB1 regulates LATS1
DDB1 regulates TAZ
UBIQUITIN interacts_with DDB1

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