Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DAX1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | DAX1 |
| Key Genes/Proteins | AGING, ALZHEIMER, ALZHEIMER'S DISEASE, KLF4, MIRNAS, NANOG |
| Related Diseases | Aging, Alzheimer |
| Related Pathways | Epigenetic, Neurogenesis |
graph TD
DAX1["DAX1"]
DAX1 -->|"regulates"| Alzheimer["Alzheimer"]
DAX1 -->|"regulates"| Aging["Aging"]
DAX1 -->|"regulates"| ALZHEIMER["ALZHEIMER"]
DAX1 -->|"regulates"| KLF4["KLF4"]
DAX1 -->|"regulates"| AND["AND"]
DAX1 -->|"regulates"| ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
DAX1 -->|"regulates"| OCT4["OCT4"]
DAX1 -->|"regulates"| MIRNAS["MIRNAS"]
SOX2["SOX2"] -->|"interacts"| DAX1
AGING["AGING"] -->|"regulates"| DAX1
NANOG["NANOG"] -->|"regulates"| DAX1
ALZHEIMER -->|"regulates"| DAX1
OCT4 -->|"regulates"| DAX1
ALZHEIMER_S_DISEASE -->|"regulates"| DAX1
KLF4 -->|"regulates"| DAX1| Target | Relation | Type | Str |
|---|---|---|---|
| Alzheimer | regulates | disease | 0.65 |
| Aging | regulates | disease | 0.65 |
| KLF4 | regulates | gene | 0.60 |
| ALZHEIMER'S DISEASE | regulates | gene | 0.60 |
| OCT4 | regulates | gene | 0.60 |
| MIRNAS | regulates | gene | 0.60 |
| Epigenetic | regulates | pathway | 0.60 |
| Neurogenesis | regulates | pathway | 0.60 |
| NANOG | regulates | gene | 0.60 |
| ALZHEIMER | regulates | gene | 0.60 |
| SOX2 | regulates | gene | 0.60 |
| AGING | regulates | gene | 0.60 |
| Stem Cell | regulates | cell_type | 0.60 |
| Stem Cell | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning DAX1 in their description or question text
No additional research found